Pharmaceutics & Novel Drug Delivery Systems

Drug Delivery and Gene Therapy

Drug delivery in cancer therapy is a rapidly evolving field that focuses on improving the effectiveness of anticancer drugs while minimizing their side effects. argeted drug delivery aims to deliver drugs specifically to cancer cells, minimizing damage to healthy cells. Various approaches, such as nanoparticles, liposomes, and antibody-drug conjugates, are used to target cancer cells based on specific markers or characteristics. Nanoparticles are widely used in cancer drug delivery due to their small size, which allows them to penetrate tumor tissue more effectively. They can be engineered to release drugs in response to specific stimuli, such as pH or enzymes present in the tumor microenvironment. Sustained-release formulations are designed to release drugs slowly over time, maintaining effective drug levels in the body. This approach can reduce the frequency of drug administration and improve patient compliance. Combination therapy, which involves the use of multiple drugs with different mechanisms of action, is common in cancer treatment. Drug delivery systems can be used to co-deliver multiple drugs, improving their synergistic effects. Drug resistance is a major challenge in cancer treatment. Drug delivery systems can help overcome resistance by delivering drugs directly to cancer cells or by delivering drugs that target specific resistance mechanisms.