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2nd International Conference and Expo on Pharmaceutics & Novel Drug Delivery Systems , will be organized around the theme “"Novel Drug Delivery Systems: Advancements and Challenges"”
Pharmaceutica-2023 is comprised of keynote and speakers sessions on latest cutting edge research designed to offer comprehensive global discussions that address current issues in Pharmaceutica-2023
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Block chains can be used to trace the origin of pharmaceuticals, the transport of drugs, and the procurement of raw materials. Block chain technology also reduces the number of intermediaries involved in the pharmaceutical process, thereby reducing costs and improving safety.
Block chain can enable companies throughout the prescription drug supply chain to verify the authenticity of medicines, expiry dates and other important information. Proponents of Block chain technology say we're on the cusp of a revolution in health care. They envision a future where doctors and institutions share medical records easily, and patients control their personal data rather than letting tech companies harvest our data for free and sell it for profit.
Digital therapeutics is a part of digital health that delivers therapeutic interventions directly to patients via evidence-based, clinically-evaluated software for disease management. Digital therapy products vary from standalone apps to complex solutions that include patient-facing software and connected medical devices. Doctor-facing app contains: List of patients with diabetes and their recent vitals (blood glucose, insulin intake, HbA1C). Notifications on abnormal health parameters. Two practical examples of digital therapy available in the market are reSET-O and Sleepio. reSET-O has various applications that lead patients with stimulant use disorders to track their substance use, cravings, and triggers.
Molecular Dynamics can be defined as a computer simulation technique that permits the prediction of time evolution of an interacting particular system involving the generation of atomic trajectories of a system using numerical integration of Newton’s equation of motion for a specific interatomic potential defined by an initial condition and boundary condition. Particularly important application of MD simulation is to determine how a biomolecular system will respond to some perturbation. In each of these cases, one should generally perform several simulations of both the perturbed and unperturbed systems in order to identify consistent differences in the results. MD simulations are used to describe the atomic and molecular properties of protein, drug-target interactions, solvation of compounds, and conformational changes that a protein or compound may undergo under various conditions. Molecular simulation methods can basically be separated into quantum mechanics (QM) methods, which treat electrons as the fundamental interactive particles of the system, and classical mechanics (CM) methods, which treat individual atoms or groups of atoms as the fundamental interactive particles of the system. Molecular simulation methods can basically be separated into quantum mechanics (QM) methods, which treat electrons as the fundamental interactive particles of the system, and classical mechanics (CM) methods, which treat individual atoms or groups of atoms as the fundamental interactive particles of the system.
Controlled drug delivery systems are conceived to release drug in a controlled manner over time. Usually the aim is to release the drug over long periods at a constant (zero-order) rate, confined to the drug's therapeutic window although in some therapies a constant release is not desirable. Controlled Drug Delivery System
- Ocular Drug Delivery System
- 2D & 3D Printing in Drug Delivery
- Drug Delivery: Devices And Equipments
Novel Drug delivery System can be referred as, approaches, formulations, technologies, and systems for transporting a pharmaceutical compound in the body as needed to safely achieve its desired therapeutic effects.
In current research, Drug delivery systems has described in four broad categories:
- Routes of delivery
- Delivery vehicles
- Targeting strategies
Noticing drug targets plays essential roles in designing novel drugs and combating diseases. Unfortunately, our current knowledge about drug targets is far from comprehensive. In the past decade, the collection of various types of study of science related data makes it possible to develop computational approaches to predict drug targets.
- Targeted drug delivery
- Drug resistance
The pharmaceutical industry is growing day by day with the introduction of new technologies but still, it is facing hurdles such as skilled professionals, increase in the development cost, protecting the new innovations.
- Medical research
- Clinical pharmaceutical scientist
- Cubist Pharmaceuticals
Pharmaceutical Microbiology is the branch of Microbiology, which involves the study of microorganisms associated with the manufacture of pharmaceuticals. e.g. controlling the number of microorganisms in a process environment, excluding microorganisms and microbial by-products like exotoxin and endotoxin from water and other starting materials, and ensures the sterile finished pharmaceutical product. Microbiology contains numerous sub-divisions which include:
Pharmaceutical Biotechnology is simply defined as, the science that covers all the technologies required for the production, manufacturing, and registration of biological drugs.
Testing large numbers of compounds to see if they produce an appropriate biochemical or cellular effect is usually one of the first steps in the drug-discovery pathway, and ways of making this screening faster, more effective and less expensive are in continual development. Designing a drug based on the targeted molecule and testing it for further modification, the testing of drugs is usually done by high-throughput screening (HTS).
- Phenotypic screening
- Virtual screening
- High-throughput screening
Pharmaceutical analysis is a process that is used for detection, determination, separation, purification, and structure elucidation of a given compound that is used in the formulation of pharmaceutical substances.
It is also called analytical chemistry that deals with the drugs both as bulk drug substances and as pharmaceutical formulations. Product analysis deals with the various formulations used for toxicological studies, clinical studies, and marketing.
Based on the determination, pharmaceutical analytical methods are of two types. They are:
- Quantitative analysis
- Qualitative analysis
Quality assurance is defined as a planned and systematic activity that is implemented within the quality system which can be demonstrated to provide confidence that a product or a service will fulfill the quality requirements. It is a system for evaluating performance, service, or the quality of a product against the system, standard or specified requirement for customers.
Biomaterials have enhanced oral and injectable drug delivery, the most common modes of drug administration, while also creating new avenues for drug delivery including via pulmonary, transdermal, ocular, and nasal routes.
The application of biomaterials in the drug delivery system has overcome the limitation we were facing in delivering drugs. It has increased the bioavailability at the site, reducing the side effect of drugs.
- Colloidal gold
- Osmotic-controlled release oral delivery system
Drug design is the process of discovering and designing new drugs, medication based on the knowledge of the targeted molecule. The drug acts as an activator/inhibitor on the biological molecule such as protein and hence in turn results in a therapeutic benefit to the affected person.
- New Drug Application
- Investigational New Drug
- Drug nomenclature
Biotherapy is also termed as Biological Therapy or Immunotherapy. It is a type of treatment that uses the substances made from living organisms such as a virus, gene, or a protein to treat a disease. Those substances may occur naturally in the body or may be made in the laboratory. Common biological agents used are:
- Tumor necrosis factor (TNF) inhibitors
- B-cell inhibitors
- Interleukins (IL) inhibitors
- Selective co-stimulation modulators
Radiopharmaceuticals are also known as medicinal radio compounds are unique medicinal formulations that contain radioisotopes. Radioisotopes are bound to biological molecules able to target specific organs, tissues, or cells within the human body. The radioactive drugs can be used in the diagnosis and, for the therapy of diseases. Radiopharmaceuticals emit radiation themselves, which is different from contrast media which alter or absorb external electromagnetism or ultrasound. Radio pharmacology is the branch of pharmacology that specializes in these agents.
Radiopharmaceuticals can be divided into four categories:
- Radiopharmaceutical preparation
- Radionuclide generator
- Radiopharmaceutical precursor
- Kit for radiopharmaceutical preparation
Pharmaceutical nanotechnology is the exciting, rapidly emerging branch of medical science that deals with harnessing nanoscale materials as drug delivery and/or diagnostic tools. As drug delivery tools, Nano-delivery systems can be used to enhance the site-specific, targeted delivery of precise medicines.
Nanomedicine provides clinically useful devices and research tools to the pharmaceutical industry. It initiates an advanced commercial application in the pharmaceutical industry which includes drug delivery system, in vivo imaging and many more.
- Impact of nanotechnology
- Virus nanotechnology
Phenotypic screening is a strategy used in drug discovery to identify molecules with the ability to alter a cell's phenotype. Animal models and cell-based assays are both strategies used to identify these molecules. It’s the process of designing of drug that will target the small molecules such as peptides, RNAi, protein molecules, which results in the alteration of the phenotype of a cell or an organism in the desired manner.
- Reverse pharmacology
- Phenotypic screening
Research in newer DDS is being carried out in liposomes, nanoparticles, niosomes, transdermal drug delivery, implants, microencapsulation, and polymers. Oral drug delivery is by far the most well-known and often the preferred route of drug administration due to its non-invasive nature, ease-of-use, cost-effectiveness, and the highly absorptive properties of the gastrointestinal (GI) tract. Advanced drug delivery technologies enhance the absorption rate of drug, efficacy and the experience of patients towards the drug.
- Thin-film drug delivery
- Nanoparticle drug delivery
- Microneedle drug delivery
It’s the study of how a human bodies react differently against drugs and drug therapies, these changes are determined by the human genetic makeup or genes. This study helps drug manufacturers and providers to choose the right amount of dose for each individual patient, which is likely to work best on that patient’s body.
- Drug labeling
The research and development (R&D) process is a critical stage in drug development in the pharmaceutical (Pharma) industry. The process starts after an initial candidate drug is identified and encompasses the rigorous research tests that determine its therapeutic suitability. Pharmaceutical Research is also called as pharmacy research. It includes within the wider area of health services research, which focuses on examining how and why people access pharmacy services, how much care costs, and what happens to patients as a result of this care.
It mostly includes:
- Drug discovery
- Drug Development,
- Drug Evaluation
- Regulatory approval of a drug
Drug development is the process of developing a new pharmaceutical drug to the market once a lead compound has been identified through the process of drug discovery. It usually includes preclinical research on microorganisms and animals, filing for regulatory status, as per the US Food and Drug Administration, for an investigational new drug to initiate clinical trials on humans, and it may include the step of obtaining regulatory approval with a new drug application to market the drug.
Pharmaceutical Formulations include Ophthalmic Formulation, Paediatric Formulation Development, Topical Formulation and Medication Formulation. Pre-Formulation and Formulation aspects which is the process in which different chemical substances i.e., active chemical substances will combine together to produce a medical compound i.e., medical drug.
- Galenic formulation
- Dosage form
Biomolecules & Therapeutics are the Strategies for Manipulating T Cells in Cancer Immunotherapy· Metabolic Bone Diseases and New Drug Developments.
- Biotherapy Treatment for Cancer
- Chemotherapy/Biotherapy Patient Education
- Biological Response Modifiers Used
- Biotherapy in Wound Treatment
- Radiopharmaceuticals in nuclear medicine
- Diagnostic radiopharmaceutical
Bio-drugs are also referred as biomedicine, Western medicine, mainstream medicine, or conventional medicine. It is a branch of medical science that applies biological and physiological principles to clinical practice. Bio-drugs are based on standardized, evidence-based treatment validated through biological research, with the treatment administered through formally trained doctors, nurses, and other such licensed practitioners.
It includes many other biomedical disciplines and areas of specialty that contain the "bio" prefix such as molecular biology, biotechnology, biochemistry, embryology, cell biology, Nanobiotechnology, biological engineering, laboratory medical biology, genetics, cytogenetics, gene therapy, systems biology, bioinformatics, biostatistics, microbiology, anatomy, toxicology, neuroscience, parasitology, virology, immunology, pathology, physiology, and many that usually concern with life sciences as applied to medicine.
A biomolecule is also known as a biological molecule. It is a used term for molecules present in organisms that are essential to one or more typically biological processes, such as cell division, morphogenesis, or development.
The four major types of biomolecules are carbohydrates, lipids, nucleic acids, and proteins.
Regulatory Affairs is involved in the development of new medicinal products from early on, by integrating regulatory principles and by preparing and submitting the relevant regulatory dossiers to health authorities. Regulatory Affairs is involved in every step of the development of a novel medicine and in the post-marketing activities with medicinal products.
- Regulatory science
- Dosage form
- Thin-film drug delivery
Medical treatments often react differently on each patients, in this case personalized medicine helps to predict the possible reaction a patient’s body might have after the administration of drug, and customized medical treatment is provided to the patient. This method is a breakthrough treatment process but it studies the patients’ unique molecular reaction to a certain disease.
- Molecular medicine
- Evidence-based medicine
- Precision Medicine Initiative