Pharmaceutics & Novel Drug Delivery Systems

Advances in Controlled Release Formulations

Controlled release formulations play a crucial role in drug delivery by providing sustained and targeted release of drugs, leading to improved efficacy and patient compliance. Nano-based drug delivery systems, such as liposomes, nanoparticles, and nanocapsules, offer controlled and targeted drug release, enhancing bioavailability and reducing side effects. These delivery systems allow for the encapsulation of drugs, providing controlled release over an extended period, suitable for both hydrophilic and hydrophobic drugs. Implantable drug delivery systems, such as drug-eluting stents and implants, provide sustained release directly at the site of action, reducing the need for frequent dosing. Hydrogels can be used to encapsulate drugs and release them in a controlled manner, offering tunable release kinetics and improved drug stability. Advances in 3D printing technology have enabled the fabrication of complex drug delivery systems with precise control over drug release rates and dosage forms. Biodegradable polymers, such as PLGA (poly(lactic-co-glycolic acid)), offer controlled drug release and are gradually broken down in the body, reducing toxicity and improving patient safety.