Day 2 :
- Drug Delivery Technologies
Session Introduction
Desalegn Feyissa Mechessa
Mizan-Tepi University, Mizan-Aman, Ethiopia
Title: Clinical pharmacist’s intervention and its acceptance rate in the pediatric ward of jimma university medical center
Biography:
Desalegn Feyissa is an esteemed researcher and lecturer hailing from Mizan-Tepi University in Ethiopia. With a wealth of knowledge and expertise, he holds the position of Assistant Professor, dedicating his efforts to shaping the minds of young scholars. Alongside his academic pursuits, Desalegn is also a passionate scientist, actively engaged in groundbreaking research. He is currently pursuing his PhD, further expanding his understanding in his chosen field. Desalegn's commitment to education and scientific exploration makes him a valuable asset to the academic community, and his contributions continue to inspire students and fellow researchers alike.
Abstract:
Drug therapy problem is associated with morbidity, mortality, increased hospital stay and reduced quality of life. Moreover, pediatric patients are quite susceptible to drug therapy problems. Clinical pharmacist services had a positive impact on pediatric patient care. To assess the prevalence of drug therapy problem, the activities of clinical pharmacists and its acceptance rate at pediatric ward of Jimma university medical center. A hospital-based cross-sectional study was conducted in the pediatric ward of Jimma University Medical Center from April 01 to June 30, 2018. The collected data were classified according to Pharmaceutical care network Europe version 5.0. Data were entered into Epi data version 4.0.2 and then exported to statistical software package version 21.0 for analysis. To identify predictors of drug therapy problems occurrence, multiple stepwise backward logistic regression analysis were done. The 95% CI was used to show the accuracy of data analysis and statistical significance was considered at P <0.05. From a total of 304 patients included in the study, nearly three fourth of them had at least on drug therapy problem per patient. A total of 356 pharmaceutical interventions were performed in the study setting. Dosing problem 112(31.46%) and drug choice problem101 (28.37%) were the predominantly identified drug therapy problem. The most important interventions provided was adherence and counseling (22.75%) followed by change of medication (13.76%). The acceptance rate of clinical pharmacist intervention was
Ali S. Alasiri
Najran University, Kingdom of Saudi Arabia
Title: Design and characterization of titanium dioxide nanoparticles utilizing green synthesis technique for diabetic wound
Biography:
Ali Alasiri is an accomplished assistant professor at the Department of Pharmaceutics, Najran University, KSA. His passion for pharmaceutical formulation led him to pursue a PhD at the esteemed De Montfort University in the UK, where he specialized in this field. With his extensive knowledge and expertise, Ali plays a crucial role in educating and mentoring aspiring pharmacists. His dedication to advancing pharmaceutical sciences and his commitment to academic excellence make him a respected figure in the field. Ali's contributions continue to shape the future of pharmaceutical research and development.
Abstract:
The current investigation aimed to design and synthesis titanium dioxide nanoparticles (TiO2.NPs) utilizing leaf extract of Ocimum sanctum for the better management of diabetic wounds. The developed Nano particulate system of average size 130.3 nm with polydispersity index 0.237 and zeta potential -11.5 mV was uniformly dispersed into chitosan gel (2% w/v) for topical application in a diabetic wound. The energy dispersive X-ray (EDX) analysis of the developed Nano particulate system exhibited strong signals of TiO2 with an intense absorption spectrum at 4-5 KeV. The streptozotocin (55 mg/kg) was used to induce diabetic wounds in Wistar rats to evaluate the wound healing efficacy of the developed formulation system compared to the marketed formulation (1% silver sulfadiazine cream). It was observed that the developed topical formulation containing TiO2.NPs have a significant (p<0.05) early epithelization time (10.25±0.5 days) compared to the control group (19.5±0.57 days) without treatment. Furthermore, histopathological investigation of the developed formulation system after wound healing (21 days) reveals improved histological development (like keratinization, hair follicles, blood vessels, and formation of granulation tissue) of skin tissue compared to the control group without treatment. The present study provided a proof-of-concept to further improve the healing efficacy of chitosan gel in combination with TiO2.NPs for diabetic wounds.